These methods were closely monitored, well planned and nutritionally balanced. Some include herbal supplements or exercise, while others focus solely on the types of food you eat. The hepatic portal vein is a vessel that moves blood from the spleen and gastrointestinal tract to the liver. The touted benefits of liver cleansing products and supplements aren’t based on evidence or fact. Most liver cleansing products and supplements are available over the counter or even on the internet.